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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
5 mg	3-5days	￥898.00	登錄后可見(jiàn)	- +
10 mg	3-5days	￥1288.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

5 mg

3-5days

￥898.00

登錄后可見(jiàn)

- +

10 mg

3-5days

￥1288.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;Resatorvid (Synonyms:TAK-242; CLI-095)
中文名稱	(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)環(huán)己-1-烯羧酸乙酯;瑞沙托維
CAS號(hào)	243984-11-4
分子式	C15H17ClFNO4S
分子量	361.82
外觀	Off-white to yellow solid
儲(chǔ)存條件	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

安全信息

產(chǎn)品詳情

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.

相關(guān)文獻(xiàn)

The anticancer effect of the TLR4 inhibition using TAK-242 (resatorvid) either as a single agent or in combination with chemotherapy: A novel therapeutic potential for breast cancer.

PMID: 31535397 DOI: 10.1002/jcb.29397

Mol Pharmacol. 2006 Apr;69(4):1288-95.

PMID: 38031141 PMCID: PMC10685467 DOI: 10.1186/s13075-023-03214-4

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(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)環(huán)己-1-烯羧酸乙酯;瑞沙托維

243984-11-4 98+% 3-5days

￥898.00 5 mg

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(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)環(huán)己-1-烯羧酸乙酯;瑞沙托維

(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;Resatorvid (Synonyms:TAK-242; CLI-095)

化學(xué)品安全說(shuō)明書(shū)(MSDS)

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