英文名稱 | Cyclosporin B |
---|---|
中文名稱 | 環(huán)孢菌素B |
CAS號 | 63775-95-1 |
分子式 | C61H109N11O12 |
分子量 | 1188.60 |
外觀 | Amorphous white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Cyclosporin B |
---|---|
中文名稱 | 環(huán)孢菌素B |
CAS號 | 63775-95-1 |
分子式 | C61H109N11O12 |
分子量 | 1188.60 |
外觀 | Amorphous white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity.