富馬酸沃諾拉贊 | 富馬酸伏諾拉生| 1260141-27-2

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Vonoprazan Fumarate | TAK-438

產品編號：CL1412 CAS No.：881681-01-2 MDLNo： 分子式：C17H16FN3O2S· C4H4O4 分子量：461.46 | 345.39 (Free)

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基本信息

英文名稱	Vonoprazan Fumarate \| TAK-438
中文名稱	富馬酸沃諾拉贊 \| 富馬酸伏諾拉生\| 1260141-27-2
CAS號	881681-01-2
分子式	C17H16FN3O2S· C4H4O4
分子量	461.46 \| 345.39 (Free)
外觀	White to off-white powder
儲存條件	4°C, sealed storage, away from moisture and light

安全信息

產品詳情

Vonoprazan Fumarate, also known as TAK438, is a new medicine for treating acid-related diseases with a novel mechanism of action called potassium-competitive acid blockers (P-CABs) which competitively inhibits the binding of potassium ions to H+,K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells. TAKECAB provides a strong and sustained acid secretion inhibitory effect.

PMID: 22512618 DOI: 10.1021/jm300318t

PMID: 20624992 DOI: 10.1124/jpet.110.170274

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CL1412

富馬酸沃諾拉贊 | 富馬酸伏諾拉生| 1260141-27-2

881681-01-2 98+%

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