替氟朵

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Tifluadom | KC 5103 | dl-Tifluadom

產品編號：CL1856 CAS No.：83386-35-0 MDLNo： 分子式：C22H20FN3OS 分子量：393.48

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基本信息

英文名稱	Tifluadom \| KC 5103 \| dl-Tifluadom
中文名稱	替氟朵
CAS號	83386-35-0
分子式	C22H20FN3OS
分子量	393.48
儲存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

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產品詳情

Tifluadom is a kappa-opioid receptor agonist. It has been shown to produce antinociception in the rotarod test and locomotor activity in mice, as well as having other pharmacological effects. Tifluadom is used to treat inflammatory disorders and autoimmune diseases. The mechanism of action of Tifluadom is not fully understood, but it may be due to its ability to bind with the benzodiazepine binding site on the GABAA receptor and also activate κ-opioid receptors. Tifluadom has been shown to increase the glomerular filtration rate (GFR) in rats by activating dopaminergic receptors that are involved in renal function.

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