英文名稱 | WP1066 |
---|---|
中文名稱 | WP1066 |
CAS號 | 857064-38-1 |
分子式 | C17H14BrN3O |
分子量 | 356.22 |
外觀 | White to off-white crystalline powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | WP1066 |
---|---|
中文名稱 | WP1066 |
CAS號 | 857064-38-1 |
分子式 | C17H14BrN3O |
分子量 | 356.22 |
外觀 | White to off-white crystalline powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.