英文名稱 | H-89 Dihydrochloride | H 89 2HCl |
---|---|
中文名稱 | H-89二鹽酸鹽 |
CAS號 | 130964-39-5 |
分子式 | C20H20BrN3O2S· 2HCl |
分子量 | 519.28 | 446.36(free) |
外觀 | White to light yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
英文名稱 | H-89 Dihydrochloride | H 89 2HCl |
---|---|
中文名稱 | H-89二鹽酸鹽 |
CAS號 | 130964-39-5 |
分子式 | C20H20BrN3O2S· 2HCl |
分子量 | 519.28 | 446.36(free) |
外觀 | White to light yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
PMID: 10998351 PMCID: PMC1221339 DOI: 10.1042/0264-6021:3510095
PMID: 21946102 DOI: 10.1016/j.ejphar.2011.09.026
PMID: 11763200 DOI: 10.1023/a:1012289526618