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規(guī)格	庫存	目錄價(jià)	會員專享價(jià)	數(shù)量
5 mg	3-5days	￥550.00	登錄后可見	- +
10 mg	3-5days	￥800.00	登錄后可見	- +
25 mg	3-5days	￥1460.00	登錄后可見	- +

規(guī)格

庫存

目錄價(jià)

會員專享價(jià)

數(shù)量

5 mg

3-5days

￥550.00

登錄后可見

- +

10 mg

3-5days

￥800.00

登錄后可見

- +

25 mg

3-5days

￥1460.00

登錄后可見

- +

基本信息

英文名稱	trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid
中文名稱	PF-04620110
CAS號	1109276-89-2
分子式	C21H24N4O4
分子量	396.44
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

PF-04620110 (PF04620110; PF 04620110) is a novel, potent, orally bioactive, and selective diglyceride acyltransferase-1 (DGAT1) inhibitor with the potential to treat type 2 diabetes mellitus. It inhibits DGAT1 with an IC50 of 19 nM. PF-04620110 has been advanced to clinical trials on the basis of the excellent pharmacologic and pharmacokinetic profiles. F-04620110 shows high selectivity versus a broad panel of off-target pharmacologic end points. In vivo DGAT-1 inhibition has been demonstrated through reduction of plasma triglyceride levels in rodents at doses of ≥0.1 mg/kg following a lipid challenge.

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瀏覽記錄

CL2505

PF-04620110

1109276-89-2 98+% 3-5days

￥550.00 5 mg

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PF-04620110

trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid

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