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規格	庫存	目錄價	會員專享價	數量
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規格

庫存

目錄價

會員專享價

數量

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基本信息

英文名稱	5-Azacytidine (Synonyms: Azacitidine; 5-AzaC; Ladakamycin)
中文名稱	阿扎胞苷 \| 5-氮雜胞苷
CAS號	320-67-2
分子式	C8H12N4O5
分子量	244.20
外觀	White to yellow powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

產品詳情

5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy.

相關文獻

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidineand 5-aza-2'-deoxycytidine.

PMID: 6173384

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

PMID: 12154409 DOI: 10.1038/sj.onc.1205699

Cytotoxicity and mode of action of 5-azacytidine on L1210 leukemia.

PMID: 5487063

5-Azacytidine and Resveratrol Enhance Chondrogenic Differentiation of Metabolic Syndrome-Derived Mesenchymal Stem Cells by Modulating Autophagy.

PMID: 31214275 PMCID: PMC6535830 DOI: 10.1155/2019/1523140