英文名稱 | Ropivacaine hydrochloride |
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中文名稱 | 鹽酸羅哌卡因 |
CAS號(hào) | 98717-15-8 |
分子式 | C17H26N2O·HCl |
分子量 | 310.86 | 274.41(free) |
外觀 | White to off-white powder |
儲(chǔ)存條件 | 4°C, sealed storage, away from moisture |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
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英文名稱 | Ropivacaine hydrochloride |
---|---|
中文名稱 | 鹽酸羅哌卡因 |
CAS號(hào) | 98717-15-8 |
分子式 | C17H26N2O·HCl |
分子量 | 310.86 | 274.41(free) |
外觀 | White to off-white powder |
儲(chǔ)存條件 | 4°C, sealed storage, away from moisture |
Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.
PMID: 25617901 PMCID: PMC4305322 DOI: 10.1371/journal.pone.0117321
Ropivacaine: a review of its use in regional anaesthesia and acute pain management.
PMID: 16392884 DOI: 10.2165/00003495-200565180-00013
PMID: 30822427 DOI: 10.1016/j.lfs.2019.02.053
PMID: 23797625 DOI: 10.1007/s00540-013-1661-1