英文名稱 | Hyperforin dicyclohexylammonium salt/Hyperforin-DCHA(Hyp-DCHA) |
---|---|
中文名稱 | 貫葉金絲桃素 二環(huán)己基銨鹽 | 貫葉金絲桃素-DCHA |
CAS號 | 238074-03-8 |
分子式 | C35H52O4·C12H23N |
分子量 | 718.10 |
外觀 | White to light yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
英文名稱 | Hyperforin dicyclohexylammonium salt/Hyperforin-DCHA(Hyp-DCHA) |
---|---|
中文名稱 | 貫葉金絲桃素 二環(huán)己基銨鹽 | 貫葉金絲桃素-DCHA |
CAS號 | 238074-03-8 |
分子式 | C35H52O4·C12H23N |
分子量 | 718.10 |
外觀 | White to light yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channel activator. Hyperforin dicyclohexylammonium salt regulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also displays a variety of bioactivities like antidepressant, antitumor, antidementia, and antidiabetic activities. Hyperforin dicyclohexylammonium salt regulates the secretion of IL-17α from γδ T cells and improves Imiquimod induced skin inflammation in psoriasis-like mice.
Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice.
Front Mol Neurosci. 2018 Dec 12;11:456.
PMID: 23875811 DOI: 10.1111/jnc.12376
PMID: 34025642 PMCID: PMC8131513 DOI: 10.3389/fimmu.2021.635076
Hyperforin: A natural lead compound with multiple pharmacological activities.
PMID: 34025642 PMCID: PMC8131513 DOI: 10.3389/fimmu.2021.635076