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首頁 > 產(chǎn)品目錄 > 信號通路 > Protein Tyrosine Kinase/RTK > DYRK > 哈爾堿; 哈爾明堿; 肉葉云香堿; 去氫駱駝蓬堿; 7-甲氧基-1-甲基-9H-吡啶并[3,4-b]吲哚

哈爾堿; 哈爾明堿; 肉葉云香堿; 去氫駱駝蓬堿; 7-甲氧基-1-甲基-9H-吡啶并[3,4-b]吲哚

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Harmine(Banisterine);7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-Methoxy-1-methyl-9H-beta-carboline;7-methoxy-1-methyl-9H-pyrido[3,4-b]indole

產(chǎn)品編號:HL1454 CAS No.:442-51-3 MDLNo: 分子式:C13H12N2O 分子量:212.25
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基本信息
英文名稱 Harmine(Banisterine);7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-Methoxy-1-methyl-9H-beta-carboline;7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
中文名稱哈爾堿; 哈爾明堿; 肉葉云香堿; 去氫駱駝蓬堿; 7-甲氧基-1-甲基-9H-吡啶并[3,4-b]吲哚
CAS號442-51-3
分子式C13H12N2O
分子量212.25
儲存條件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Harmine (telepathine) is a naturally occuring beta-carboline and fluorescent harmala alkaloid found in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (formerly known as 'yage' or 'ayahuasca'). Harmine is a RIMA because it reversibly inhibits the enzyme monoamine oxidase A (MAO-A), which breaks down monoamines. While it does not inhibit the MAO-B variant, harmine binds to MAO-A specifically. In addition, it is an inhibitor of tyrosine phosphorylation-regulated kinase (DYRK) with anti-inflammatory and anti-cancer properties. With a Ki of 397 nM, harmine exhibits a high affinity for the 5-HT2A serotonin receptor.

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