英文名稱 | Sivelestat Sodium Anhydrous | ONO5046-Na | Sodium sivelestat | EI546 sodium | LY544349 sodium |
---|---|
中文名稱 | 西維來司鈉 |
CAS號 | 150374-95-1 |
分子式 | C20H21N2NaO7S |
分子量 | 456.44 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | 4°C, sealed storage, away from moisture |
規(guī)格 | 庫存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | Sivelestat Sodium Anhydrous | ONO5046-Na | Sodium sivelestat | EI546 sodium | LY544349 sodium |
---|---|
中文名稱 | 西維來司鈉 |
CAS號 | 150374-95-1 |
分子式 | C20H21N2NaO7S |
分子量 | 456.44 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | 4°C, sealed storage, away from moisture |
Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun.
PMID: 2049103 DOI: 10.1016/0006-291x(91)91862-7
PMID: 18165924 DOI: 10.1007/s11010-007-9698-9